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C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy

C3 glomerulopathy is a potentially life-threatening disease of the kidney caused by dysregulated alternative pathway complement activation. The specific complement mediator(s) responsible for kidney injury in C3 glomerulopathy are yet to be defined and no specific therapy is currently available. We...

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Bibliographic Details
Published in:Kidney Int
Main Authors: Williams, Allison Lesher, Gullipalli, Damodar, Ueda, Yoshiyasu, Sato, Sayaka, Zhou, Lin, Miwa, Takashi, Tung, Kenneth S., Song, Wen-Chao
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429978/
https://ncbi.nlm.nih.gov/pubmed/28139294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.11.018
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