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C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy

C3 glomerulopathy is a potentially life-threatening disease of the kidney caused by dysregulated alternative pathway complement activation. The specific complement mediator(s) responsible for kidney injury in C3 glomerulopathy are yet to be defined and no specific therapy is currently available. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Kidney Int
Hauptverfasser: Williams, Allison Lesher, Gullipalli, Damodar, Ueda, Yoshiyasu, Sato, Sayaka, Zhou, Lin, Miwa, Takashi, Tung, Kenneth S., Song, Wen-Chao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429978/
https://ncbi.nlm.nih.gov/pubmed/28139294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.11.018
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