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Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily

Background C3 glomerulopathy (C3G) is a life-threatening kidney disease caused by dysregulation of the alternative pathway of complement (AP) activation. No approved specific therapy is available for C3G, although an anti-C5 mAb has been used off-label in some patients with C3G, with mixed results....

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Wang, Xiaoxu, Van Lookeren Campagne, Menno, Katschke, Kenneth J., Gullipalli, Damodar, Miwa, Takashi, Ueda, Yoshiyasu, Wang, Yuan, Palmer, Matthew, Xing, Guolan, Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065080/
https://ncbi.nlm.nih.gov/pubmed/29895552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018030270
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