Deficiency of decay-accelerating factor and complement receptor 1–related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg

Complement activation on human platelets is known to cause platelet degranulation and activation. To evaluate how normal platelets escape complement attack in vivo, we studied the fate of murine platelets deficient in 2 membrane complement regulatory proteins using an adoptive transfer model. We sho...

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Detalhes bibliográficos
Main Authors: Kim, David D., Miwa, Takashi, Kimura, Yuko, Schwendener, Reto A., van Lookeren Campagne, Menno, Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515136/
https://ncbi.nlm.nih.gov/pubmed/18524992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134304
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