CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement

Although CRIg was originally identified as a macrophage receptor for binding complement C3b/iC3b in vitro, recent studies reveal that CRIg functions as a pattern recognition receptor in vivo for Kupffer cells (KCs) to directly bind bacterial pathogens in a complement-independent manner. This raises...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Liu, Gongguan, Fu, Yong, Yosri, Mohammed, Chen, Yanli, Sun, Peng, Xu, Jinjun, Zhang, Mingshun, Sun, Donglei, Strickland, Ashley B., Mackey, Zachary B., Shi, Meiqing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883839/
https://ncbi.nlm.nih.gov/pubmed/31723045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913443116
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