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Real-Time Imaging of Interactions of Neutrophils with Cryptococcus neoformans Demonstrates a Crucial Role of Complement C5a-C5aR Signaling

Neutrophils have been shown to efficiently kill Cryptococcus neoformans, a causative agent of meningoencephalitis. Here, using live-cell imaging, we characterize the dynamic interactions of neutrophils with C. neoformans and the underlying mechanisms in real time. Neutrophils were directly seen to c...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Sun, Donglei, Zhang, Mingshun, Liu, Gongguan, Wu, Hui, Zhu, Xiaoping, Zhou, Hong, Shi, Meiqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693990/
https://ncbi.nlm.nih.gov/pubmed/26502909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01197-15
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