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C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy

C3 glomerulopathy is a potentially life-threatening disease of the kidney caused by dysregulated alternative pathway complement activation. The specific complement mediator(s) responsible for kidney injury in C3 glomerulopathy are yet to be defined and no specific therapy is currently available. We...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Williams, Allison Lesher, Gullipalli, Damodar, Ueda, Yoshiyasu, Sato, Sayaka, Zhou, Lin, Miwa, Takashi, Tung, Kenneth S., Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429978/
https://ncbi.nlm.nih.gov/pubmed/28139294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.11.018
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