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Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer

Long non-coding RNAs (lncRNAs) play key roles in human diseases, including cancer. Functional studies of the lncRNA HOTAIR (HOX transcript antisense RNA) provide compelling evidence for therapeutic targeting of HOTAIR in cancer, but targeting lncRNAs in vivo has proven to be difficult. In the curren...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Özeş, Ali R., Wang, Yinu, Zong, Xingyue, Fang, Fang, Pilrose, Jay, Nephew, Kenneth P.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429858/
https://ncbi.nlm.nih.gov/pubmed/28420874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00966-3
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