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Targeting Ovarian Cancer Stem Cells by Dual Inhibition of HOTAIR and DNA Methylation

Ovarian cancer is a chemoresponsive tumor with very high initial response rates to standard therapy consisting of platinum/paclitaxel. However, most women eventually develop recurrence, which rapidly evolves into chemo-resistant disease. Persistence of ovarian cancer stem cells (OCSC) at the end of...

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Pubblicato in:Mol Cancer Ther
Autori principali: Wang, Weini, Fang, Fang, Ozes, Ali, Nephew, Kenneth P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172444/
https://ncbi.nlm.nih.gov/pubmed/33785648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0826
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