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NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) play diverse functional roles in cancer. In this study, we show that upregulation of HOTAIR induced platinum resistance in ovarian cancer, and increased HOTAIR levels we...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050052/ https://ncbi.nlm.nih.gov/pubmed/27041570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.75 |
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