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The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma

This article focusses on the role of TGF-β and its signaling crosstalk with the RHO family GTPases RAC1 and RAC1b in the progression of breast and pancreatic carcinoma. The aggressive nature of these tumor types is mainly due to metastatic dissemination. Metastasis is facilitated by desmoplasia, a p...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Melzer, Catharina, Hass, Ralf, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429551/
https://ncbi.nlm.nih.gov/pubmed/28499439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0175-0
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