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The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma

This article focusses on the role of TGF-β and its signaling crosstalk with the RHO family GTPases RAC1 and RAC1b in the progression of breast and pancreatic carcinoma. The aggressive nature of these tumor types is mainly due to metastatic dissemination. Metastasis is facilitated by desmoplasia, a p...

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Publicat a:Cell Commun Signal
Autors principals: Melzer, Catharina, Hass, Ralf, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429551/
https://ncbi.nlm.nih.gov/pubmed/28499439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0175-0
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