CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool

Cre-loxP, as one of the site-specific genetic manipulation tools, offers a method to study the spatial and temporal regulation of gene expression/inactivation in order to decipher gene function. CRISPR/Cas9-mediated targeted genome engineering technologies are sparking a new revolution in biological...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Yang, Fayu, Liu, Changbao, Chen, Ding, Tu, Mengjun, Xie, Haihua, Sun, Huihui, Ge, Xianglian, Tang, Lianchao, Li, Jin, Zheng, Jiayong, Song, Zongming, Qu, Jia, Gu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429228/
https://ncbi.nlm.nih.gov/pubmed/28624213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.04.018
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