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Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions

The development of in vitro models for the maintenance and differentiation of pluripotent stem cells (PSCs) is an active area of stem cell research. The strategies used so far are based mainly on two-dimensional (2D) cultures, in which cellular phenotypes are regulated by soluble factors. We show th...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Zujur, Denise, Kanke, Kosuke, Lichtler, Alexander C., Hojo, Hironori, Chung, Ung-il, Ohba, Shinsuke
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429032/
https://ncbi.nlm.nih.gov/pubmed/28508073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602875
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