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Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions

The development of in vitro models for the maintenance and differentiation of pluripotent stem cells (PSCs) is an active area of stem cell research. The strategies used so far are based mainly on two-dimensional (2D) cultures, in which cellular phenotypes are regulated by soluble factors. We show th...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zujur, Denise, Kanke, Kosuke, Lichtler, Alexander C., Hojo, Hironori, Chung, Ung-il, Ohba, Shinsuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429032/
https://ncbi.nlm.nih.gov/pubmed/28508073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602875
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