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Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions

The development of in vitro models for the maintenance and differentiation of pluripotent stem cells (PSCs) is an active area of stem cell research. The strategies used so far are based mainly on two-dimensional (2D) cultures, in which cellular phenotypes are regulated by soluble factors. We show th...

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Pubblicato in:Sci Adv
Autori principali: Zujur, Denise, Kanke, Kosuke, Lichtler, Alexander C., Hojo, Hironori, Chung, Ung-il, Ohba, Shinsuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429032/
https://ncbi.nlm.nih.gov/pubmed/28508073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602875
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