PAR1-mediated c-Jun activation promotes heat stress-induced early stage apoptosis of human umbilical vein endothelial cells

Our previous study indicated that when human umbilical vein endothelial cells (HUVECs), which are involved in endothelial barrier function, are heat stressed, levels of protease-activated receptor 1 (PAR1) are increased significantly. In the present study, it was demonstrated that PAR1 serves a vita...

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Publicado en:Mol Med Rep
Main Authors: Zhang, Shuang, Liu, Yanan, Wang, Zhenglian, Liu, Jingxian, Gu, Zhengtao, Xu, Qiulin, Su, Lei
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2017
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428901/
https://ncbi.nlm.nih.gov/pubmed/28447716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6303
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