PAR1-mediated c-Jun activation promotes heat stress-induced early stage apoptosis of human umbilical vein endothelial cells

Our previous study indicated that when human umbilical vein endothelial cells (HUVECs), which are involved in endothelial barrier function, are heat stressed, levels of protease-activated receptor 1 (PAR1) are increased significantly. In the present study, it was demonstrated that PAR1 serves a vita...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Zhang, Shuang, Liu, Yanan, Wang, Zhenglian, Liu, Jingxian, Gu, Zhengtao, Xu, Qiulin, Su, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428901/
https://ncbi.nlm.nih.gov/pubmed/28447716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6303
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