Heat Stress-Induced Disruption of Endothelial Barrier Function Is via PAR1 Signaling and Suppressed by Xuebijing Injection

Increased vascular permeability leading to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is central to the pathogenesis of heatstroke. Protease-activated receptor 1 (PAR1), the receptor for thrombin, plays a key role in disruption of endothelial barrier function in response...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xu, Qiulin, Liu, Jingxian, Wang, Zhenglian, Guo, Xiaohua, Zhou, Gengbiao, Liu, Yanan, Huang, Qiaobing, Su, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334482/
https://ncbi.nlm.nih.gov/pubmed/25693178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118057
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