Heat Stress-Induced Disruption of Endothelial Barrier Function Is via PAR1 Signaling and Suppressed by Xuebijing Injection

Increased vascular permeability leading to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is central to the pathogenesis of heatstroke. Protease-activated receptor 1 (PAR1), the receptor for thrombin, plays a key role in disruption of endothelial barrier function in response...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Xu, Qiulin, Liu, Jingxian, Wang, Zhenglian, Guo, Xiaohua, Zhou, Gengbiao, Liu, Yanan, Huang, Qiaobing, Su, Lei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334482/
https://ncbi.nlm.nih.gov/pubmed/25693178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118057
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