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Reactive oxygen species mediate heat stress-induced apoptosis via ERK dephosphorylation and Bcl-2 ubiquitination in human umbilical vein endothelial cells

Heat stress can induce the mitochondrial apoptotic pathway in HUVEC cells, indicating that apoptosis may be a prominent pathological feature of heat stroke, however, little is known about the precise mechani sms involved in it. In this study, we describe the apoptotic effect of intense heat stress o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Li, Tan, Hongping, Yang, Hong, Li, Feng, He, Xuan, Gu, Zhengtao, Zhao, Ming, Su, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355065/
https://ncbi.nlm.nih.gov/pubmed/28038454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14186
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