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Reactive oxygen species mediate heat stress-induced apoptosis via ERK dephosphorylation and Bcl-2 ubiquitination in human umbilical vein endothelial cells

Heat stress can induce the mitochondrial apoptotic pathway in HUVEC cells, indicating that apoptosis may be a prominent pathological feature of heat stroke, however, little is known about the precise mechani sms involved in it. In this study, we describe the apoptotic effect of intense heat stress o...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Li, Li, Tan, Hongping, Yang, Hong, Li, Feng, He, Xuan, Gu, Zhengtao, Zhao, Ming, Su, Lei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355065/
https://ncbi.nlm.nih.gov/pubmed/28038454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14186
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