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Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation

Uhrf1-dependent histone H3 ubiquitylation plays a crucial role in the maintenance of DNA methylation via the recruitment of the DNA methyltransferase Dnmt1 to DNA methylation sites. However, the involvement of deubiquitylating enzymes (DUBs) targeting ubiquitylated histone H3 in the maintenance of D...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamaguchi, Luna, Nishiyama, Atsuya, Misaki, Toshinori, Johmura, Yoshikazu, Ueda, Jun, Arita, Kyohei, Nagao, Koji, Obuse, Chikashi, Nakanishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427934/
https://ncbi.nlm.nih.gov/pubmed/28246399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00136-5
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