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Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

Ubiquitin-specific peptidase 42 (USP42) is a deubiquitylating enzyme that can target p53 and contribute to the stabilization of p53 in response to stress. We now show that USP42 can also regulate transcription independently of p53. USP42 co-localized with RNA polymerase II (RNA Pol II) in nuclear fo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hock, Andreas K., Vigneron, Arnaud M., Vousden, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263885/
https://ncbi.nlm.nih.gov/pubmed/25336640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589267
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