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Multiple facets of p53 in senescence induction and maintenance

Cellular senescence is a state of durable cell cycle arrest with metabolic activities distinct from those of the proliferative state. Since senescence was originally reported to be induced by various genotoxic stressors, such as telomere erosion and oncogenic signaling, it has been proposed to play...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Johmura, Yoshikazu, Nakanishi, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132285/
https://ncbi.nlm.nih.gov/pubmed/27560979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13060
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