Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation

Purpose: Implication of protein-protein interactions (PPIs) in development of many diseases such as cancer makes them attractive for therapeutic intervention and rational drug design. RON (Recepteur d’Origine Nantais) tyrosine kinase receptor has gained considerable attention as promising target in...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Zarei, Omid, Hamzeh-Mivehroud, Maryam, Benvenuti, Silvia, Ustun-Alkan, Fulya, Dastmalchi, Siavoush
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426727/
https://ncbi.nlm.nih.gov/pubmed/28507948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2017.018
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