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Prediction of Hot Spots at Myeloid Cell Leukemia-1–Inhibitor Interface Using Energy Estimation and Alanine Scanning Mutagenesis
[Image: see text] Myeloid cell leukemia 1 (Mcl1) is an antiapoptotic protein that plays central role in apoptosis regulation. Also, Mcl1 has the potency to resist apoptotic cues resulting in up-regulation and cancer cell protection. A molecular probe that has the potential to specifically target Mcl...
Kaydedildi:
| Yayımlandı: | Biochemistry |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American
Chemical Society
2018
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6203182/ https://ncbi.nlm.nih.gov/pubmed/29345906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01048 |
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