In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies

Interference with microtubule polymerization results in cell cycle arrest leading to cell death. Colchicine is a well-known microtubule polymerization inhibitor which does so by binding to a specific site on tubulin. A set of 3', 4'-bis (substituted phenyl)-4'H-spiro [indene-2, 5'...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Iran J Pharm Res
Hlavní autoři: Abolhasani, Hoda, Zarghi, Afshin, Hamzeh-Mivehroud, Maryam, Alizadeh, Ali Akbar, Shahbazi Mojarrad, Javid, Dastmalchi, Siavoush
Médium: Artigo
Jazyk:Inglês
Vydáno: Shaheed Beheshti University of Medical Sciences 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277627/
https://ncbi.nlm.nih.gov/pubmed/25561920
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky