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An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

Purpose: Receptor tyrosine kinase (RTK) inhibitors are widely used pharmaceuticals in cancer therapy. Fibroblast growth factor receptors (FGFRs) are members of RTK superfamily which are highly expressed on the surface of carcinoma associate fibroblasts (CAFs). The involvement of FGFRs in different t...

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Dades bibliogràfiques
Publicat a:Adv Pharm Bull
Autors principals: Jafari, Behzad, Hamzeh-Mivehroud, Maryam, Alizadeh, Ali Akbar, Sharifi, Mehdi, Dastmalchi, Siavoush
Format: Artigo
Idioma:Inglês
Publicat: Tabriz University of Medical Sciences 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651062/
https://ncbi.nlm.nih.gov/pubmed/29071223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2017.049
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