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An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

Purpose: Receptor tyrosine kinase (RTK) inhibitors are widely used pharmaceuticals in cancer therapy. Fibroblast growth factor receptors (FGFRs) are members of RTK superfamily which are highly expressed on the surface of carcinoma associate fibroblasts (CAFs). The involvement of FGFRs in different t...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Jafari, Behzad, Hamzeh-Mivehroud, Maryam, Alizadeh, Ali Akbar, Sharifi, Mehdi, Dastmalchi, Siavoush
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651062/
https://ncbi.nlm.nih.gov/pubmed/29071223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2017.049
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