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In silico Evaluation of Crosslinking Effects on Denaturant m (eq) values and ΔCp upon Protein Unfolding
Important thermodynamic parameters including denaturant equilibrium m values (m (eq)) and heat capacity changes (ΔCp) can be predicted based on changes in Solvent Accessible Surface Area (SASA) upon unfolding. Crosslinks such as disulfide bonds influence the stability of the proteins by decreasing t...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Avicenna Research Institute
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558204/ https://ncbi.nlm.nih.gov/pubmed/23408172 |
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