Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin

The cellular serine protease TMPRSS2, a member of the type II transmembrane serine protease (TTSP) family, cleaves and activates the hemagglutinin of influenza A viruses (FLUAV) in cell culture and is essential for spread of diverse FLUAV in mice. Non-human primates (NHP), in particular rhesus and c...

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Publicado no:PLoS One
Main Authors: Zmora, Pawel, Molau-Blazejewska, Paulina, Bertram, Stephanie, Walendy-Gnirß, Kerstin, Nehlmeier, Inga, Hartleib, Anika, Moldenhauer, Anna-Sophie, Konzok, Sebastian, Dehmel, Susann, Sewald, Katherina, Brinkmann, Constantin, Curths, Christoph, Knauf, Sascha, Gruber, Jens, Mätz-Rensing, Kerstin, Dahlmann, Franziska, Braun, Armin, Pöhlmann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426610/
https://ncbi.nlm.nih.gov/pubmed/28493964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176597
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