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TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells
The cellular protease TMPRSS2 cleaves and activates the influenza virus hemagglutinin (HA) and TMPRSS2 expression is essential for viral spread and pathogenesis in mice. Moreover, severe acute respiratory syndrome coronavirus (SARS-CoV) and other respiratory viruses are activated by TMPRSS2. However...
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| Vydáno v: | PLoS One |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4574978/ https://ncbi.nlm.nih.gov/pubmed/26379044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138380 |
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