IGFBP-4 regulates adult skeletal growth in a sex-specific manner

Insulin-like growth factor-1 (IGF-1) and its binding proteins are critical mediators of skeletal growth. Insulin-like growth factor-binding protein 4 (IGFBP-4) is highly expressed in osteoblasts and inhibits IGF-1 actions in vitro. Yet, in vivo studies suggest that it could potentiate IGF-1 and IGF-...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Maridas, David E, DeMambro, Victoria E, Le, Phuong T, Nagano, Kenichi, Baron, Roland, Mohan, Subburaman, Rosen, Clifford J
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425953/
https://ncbi.nlm.nih.gov/pubmed/28184001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0673
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