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IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots
Insulinlike growth factor (IGF) I induces adipogenesis in vitro. IGF-binding protein 4 (IGFBP4) is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. We previously reported that Igfbp4 null mice (Igfbp4(−/−)) had decreased fat proportions at 8 and 16 weeks of age. How...
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| Publicado no: | Endocrinology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659704/ https://ncbi.nlm.nih.gov/pubmed/28938423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00248 |
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