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IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots

Insulinlike growth factor (IGF) I induces adipogenesis in vitro. IGF-binding protein 4 (IGFBP4) is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. We previously reported that Igfbp4 null mice (Igfbp4(−/−)) had decreased fat proportions at 8 and 16 weeks of age. How...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Endocrinology
मुख्य लेखकों: Maridas, David E., DeMambro, Victoria E., Le, Phuong T., Mohan, Subburaman, Rosen, Clifford J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Endocrine Society 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659704/
https://ncbi.nlm.nih.gov/pubmed/28938423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00248
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