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Gender-Specific Changes in Bone Turnover and Skeletal Architecture in Igfbp-2-Null Mice
IGF-binding protein-2 (IGFBP-2) is a 36-kDa protein that binds to the IGFs with high affinity. To determine its role in bone turnover, we compared Igfbp2(−/−) mice with Igfbp2(+/+) colony controls. Igfbp2(−/−) males had shorter femurs and were heavier than controls but were not insulin resistant. Se...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Endocrine Society
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329262/ https://ncbi.nlm.nih.gov/pubmed/18276763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1068 |
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