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Interdependence of Inhibitor Recognition in HIV-1 Protease

[Image: see text] Molecular recognition is a highly interdependent process. Subsite couplings within the active site of proteases are most often revealed through conditional amino acid preferences in substrate recognition. However, the potential effect of these couplings on inhibition and thus inhib...

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Pubblicato in:J Chem Theory Comput
Autori principali: Paulsen, Janet L., Leidner, Florian, Ragland, Debra A., Kurt Yilmaz, Nese, Schiffer, Celia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425943/
https://ncbi.nlm.nih.gov/pubmed/28358514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01262
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