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Interdependence of Inhibitor Recognition in HIV-1 Protease

[Image: see text] Molecular recognition is a highly interdependent process. Subsite couplings within the active site of proteases are most often revealed through conditional amino acid preferences in substrate recognition. However, the potential effect of these couplings on inhibition and thus inhib...

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Bibliographische Detailangaben
Veröffentlicht in:J Chem Theory Comput
Hauptverfasser: Paulsen, Janet L., Leidner, Florian, Ragland, Debra A., Kurt Yilmaz, Nese, Schiffer, Celia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425943/
https://ncbi.nlm.nih.gov/pubmed/28358514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01262
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