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Interdependence of Inhibitor Recognition in HIV-1 Protease

[Image: see text] Molecular recognition is a highly interdependent process. Subsite couplings within the active site of proteases are most often revealed through conditional amino acid preferences in substrate recognition. However, the potential effect of these couplings on inhibition and thus inhib...

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Bibliografiske detaljer
Udgivet i:J Chem Theory Comput
Main Authors: Paulsen, Janet L., Leidner, Florian, Ragland, Debra A., Kurt Yilmaz, Nese, Schiffer, Celia A.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425943/
https://ncbi.nlm.nih.gov/pubmed/28358514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01262
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