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Interdependence of Inhibitor Recognition in HIV-1 Protease

[Image: see text] Molecular recognition is a highly interdependent process. Subsite couplings within the active site of proteases are most often revealed through conditional amino acid preferences in substrate recognition. However, the potential effect of these couplings on inhibition and thus inhib...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Paulsen, Janet L., Leidner, Florian, Ragland, Debra A., Kurt Yilmaz, Nese, Schiffer, Celia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425943/
https://ncbi.nlm.nih.gov/pubmed/28358514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01262
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