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Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization

The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear. Here, we report that the duration of mitosis in haploid E...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Guo, Ao, Huang, Shichao, Yu, Jiali, Wang, Huihan, Li, Haisen, Pei, Gang, Shen, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425685/
https://ncbi.nlm.nih.gov/pubmed/28457886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.03.025
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