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Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.

Islet amyloid polypeptide (IAPP), a putative polypeptide hormone, is a product of pancreatic beta-cells and the major constituent of the amyloid deposits seen mainly in islets of type 2 diabetic humans and diabetic cats. The connection between IAPP amyloid formation and diabetes is unknown, but a li...

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Autors principals: Westermark, P, Engström, U, Johnson, K H, Westermark, G T, Betsholtz, C
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC54256/
https://ncbi.nlm.nih.gov/pubmed/2195544
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