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Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH

Visualization of chromosome dynamics allows the investigation of spatiotemporal chromatin organization and its role in gene regulation and other cellular processes. However, current approaches to label multiple genomic loci in live cells have a fundamental limitation in the number of loci that can b...

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Vydáno v:Biophys J
Hlavní autoři: Takei, Yodai, Shah, Sheel, Harvey, Sho, Qi, Lei S., Cai, Long
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425380/
https://ncbi.nlm.nih.gov/pubmed/28427715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.024
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