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Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH

Visualization of chromosome dynamics allows the investigation of spatiotemporal chromatin organization and its role in gene regulation and other cellular processes. However, current approaches to label multiple genomic loci in live cells have a fundamental limitation in the number of loci that can b...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Takei, Yodai, Shah, Sheel, Harvey, Sho, Qi, Lei S., Cai, Long
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425380/
https://ncbi.nlm.nih.gov/pubmed/28427715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.024
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