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Selective anomeric acetylation of unprotected sugars in water

High yielding selective acetylation of only the anomeric hydroxyl of unprotected sugars is possible in aqueous solution using 2-chloro-1,3-dimethylimidazolinium chloride (DMC), thioacetic acid, and a suitable base. The reaction, which may be performed on a multi-gram scale, is stereoselective for su...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Lim, David, Fairbanks, Antony J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424810/
https://ncbi.nlm.nih.gov/pubmed/28553480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04667c
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