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Creation of the first anomeric d/l-sugar kinase by means of directed evolution

Chemoenzymatic routes toward complex glycoconjugates often depend on the availability of sugar-1-phosphates. Yet the chemical synthesis of these vital components is often tedious, whereas natural enzymes capable of anomeric phosphorylation are known to be specific for one or only a few monosaccharid...

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Autors principals: Hoffmeister, Dirk, Yang, Jie, Liu, Lesley, Thorson, Jon S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC263743/
https://ncbi.nlm.nih.gov/pubmed/14612558
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