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Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction
[Image: see text] Ammonia in the tetrazole Ugi variation together with α-amino acid methyl ester-derived isocyanides provides tetrazolopiperidinones in good to high yields in one pot. The scope and limitations of this reaction were investigated by performing >70 reactions. The scaffold is useful...
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| Gepubliceerd in: | ACS Comb Sci |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2017
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5424440/ https://ncbi.nlm.nih.gov/pubmed/28240545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.7b00033 |
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