Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR

[Image: see text] The synthesis of uracil/thymine containing tetra/trisubstituted imidazole derivatives was demonstrated using Ugi/Passerini-reaction followed by a postcyclization reaction sequence. The approach enables the one-pot facile construction of diverse compounds in moderate to excellent yi...

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Foilsithe in:ACS Comb Sci
Main Authors: Madhavachary, Rudrakshula, Zarganes-Tzitzikas, Tryfon, Patil, Pravin, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2018
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894062/
https://ncbi.nlm.nih.gov/pubmed/29457887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.7b00145
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