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CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond

Chimeric antigen receptors (CARs) are versatile synthetic receptors that provide T cells with engineered specificity. Clinical success in treating B-cell malignancies has demonstrated the therapeutic potential of CAR-T cells against cancer, and efforts are underway to expand the use of engineered T...

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Publicat a:Trends Mol Med
Autors principals: Chang, ZeNan L., Chen, Yvonne Y.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423782/
https://ncbi.nlm.nih.gov/pubmed/28416139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2017.03.002
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