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Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands
The expression of synthetic receptors in primary T cells enables the programming of user-defined responses when designing T-cell therapies. Chimeric antigen receptors (CARs) are synthetic receptors that have demonstrated efficacy in cancer therapy by targeting immobilized antigens on the surface of...
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| Publicado no: | Nat Protoc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7430204/ https://ncbi.nlm.nih.gov/pubmed/32103205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-0294-8 |
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