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Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors
BACKGROUND: T cells expressing chimeric antigen receptors (CARs) have shown exciting promise in cancer therapy, particularly in the treatment of B-cell malignancies. However, optimization of CAR-T cell production remains a trial-and-error exercise due to a lack of phenotypic benchmarks that are clea...
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| Publicado no: | J Transl Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457995/ https://ncbi.nlm.nih.gov/pubmed/25990251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0519-8 |
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