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Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors

BACKGROUND: T cells expressing chimeric antigen receptors (CARs) have shown exciting promise in cancer therapy, particularly in the treatment of B-cell malignancies. However, optimization of CAR-T cell production remains a trial-and-error exercise due to a lack of phenotypic benchmarks that are clea...

詳細記述

保存先:
書誌詳細
出版年:J Transl Med
主要な著者: Chang, ZeNan L., Silver, Pamela A., Chen, Yvonne Y.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457995/
https://ncbi.nlm.nih.gov/pubmed/25990251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0519-8
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