Učitavanje...
Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression
Chimeric antigen receptor (CAR) T cell therapy is an effective method for treating specific cancers. CARs are normally designed to recognize antigens, which are highly expressed on malignant cells but not on T cells. However, when T cells are engineered with CARs that recognize antigens expressed on...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794762/ https://ncbi.nlm.nih.gov/pubmed/29391449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02912-x |
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