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TGF‐β–responsive CAR‐T cells promote anti‐tumor immune function
A chimeric antigen receptor (CAR) that responds to transforming growth factor beta (TGF‐β) enables the engineering of T cells that convert this immunosuppressive cytokine into a potent T‐cell stimulant. However, clinical translation of TGF‐β CAR‐T cells for cancer therapy requires the ability to pro...
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| Publicado no: | Bioeng Transl Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063867/ https://ncbi.nlm.nih.gov/pubmed/30065964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10097 |
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